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Efavirenz Switch to brand medication Drug Info Side Effects Dosage Medicare Specialty drug How to get this medication Generic Sustiva is a specialty medication, which can cost more than standard prescriptions and involve a few extra steps. We'll help you understand what to expect. Sustiva can interact with various medications, including certain antibiotics, antifungals, antidepressants, and anticonvulsants. Inform your healthcare provider about all the medications you are currently taking, including prescription, over the counter, herbal, or dietary supplements, to avoid potential interactions. Drug interactions: Sustiva can interact with other medications, including over-the-counter drugs, herbal supplements, and prescription medications. It is crucial to inform your doctor about all the medications you are taking to avoid potentially harmful interactions. Viagra is a popular treatment for ED, but it's not the only option. 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