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It works by blocking substances in the body that may cause nausea or vomiting. It belongs to a group of medications called antiemetics. Zofran (ondansetron) is an antiemetic prescription that helps manage nausea and vomiting. Request Zofran from one of our board-certified doctors online. Get a Zofran (ondansetron) prescription online for nausea and vomiting. Licensed providers, same-day telehealth evaluations available. Generic tablets and ODT forms. A medication's strength can be found on your medication's bottle, packaging, or instructions. This number represents the amount of a drug in dosage form—for example, a 50mg tablet. If you don't know your medication's strength, contact your prescriber or current pharmacy. Get Zofran Online Zofran (ondansetron) is a prescription antiemetic used to prevent and treat nausea and vomiting. Get evaluated by a licensed physician online and receive a treatment plan without leaving home. 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